New Book (2026): An Evolutionary Story of Agency

3 October 2025

New Book (2026): An Evolutionary Story of Agency

In this new book, Alvaro Moreno and Juli Peretó look at the major transitions in the history of biological agency, from the origins of life to the complexity of Metazoans, and its role in the complexification of biological organization in the history of life. Available open-access here. About this book This open access book exposes […]

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New video interview with Ezequiel Di Paolo on biological, sensorimotor and social autonomy

10 July 2025

New video interview with Ezequiel Di Paolo on biological, sensorimotor and social autonomy

Already in the early 2000s, Francisco Varela and Evan Thompson emphasized that the notion of autonomy should be understood as scaffolded along multiple, entangled, and overlapping dimensions—namely, biological regulation, sensorimotor coupling, and social interaction. Since then, various developments of the autonomy framework have sought to articulate this multidimensionality. The enactive approach, particularly the version proposed […]

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New edition of Principles of Biological Autonomy

17 June 2025

New edition of Principles of Biological Autonomy

Today, we celebrate the new publication of Principles of Biological Autonomy (1979) by MIT Press, now accompanied by a new critical apparatus by Ezequiel Di Paolo and Evan Thompson.Varela’s ideas continue to shape cognitive science through the ongoing development of the enactive approach, which today encompasses accounts of various aspects of cognition and is becoming […]

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New Paper (2025): Closure of Constraints as a Theoretical Model

4 February 2025

New Paper (2025): Closure of Constraints as a Theoretical Model

Published open access in Philosophy of Science. Abstract: In this paper I offer a model-theoretic interpretation of Autonomy Theory as defended by Moreno, Mossio, Montévil, and Bich. I address accusations that Autonomy Theory is excessively liberal, such as those made by Garson (2017), arguing that these misunderstand the role of strategic abstractions and generalizations in […]

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Paper (2024): Closure of Constraints and the Individuation of Causal Systems in Biology

30 January 2025

Paper (2024): Closure of Constraints and the Individuation of Causal Systems in Biology

Published as part of The Routledge Handbook of Causality and Causal Methods and available open access here. Abstract: In order to carry out many scientific practices, say, doing measurements, building explanations, planning interventions, it is necessary to identify which causal systems will be measured, explained or intervened upon. Accordingly, it is important in biological research […]

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New book: Biological Organization

7 December 2024

New book: Biological Organization

Author: Leonardo Bich Date of publication: 04 December 2024 Publisher: Cambridge University Press The PDF version of this book is available here. Summary Living systems are complex systems made of components that tend to degrade, but nonetheless they maintain themselves far from equilibrium. This requires living systems to extract energy and materials from the environment […]

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New Paper (2024): Organizational teleology 2.0: Grounding biological purposiveness in regulatory control

28 May 2024

New Paper (2024): Organizational teleology 2.0: Grounding biological purposiveness in regulatory control

Published open-access in Ratio. Abstract: This paper critically revises the organisational account of teleology, which argues that living systems are first and foremost oriented towards a goal: maintaining their own conditions of existence. It points out some limitations of this account, mainly in the capability to account for the richness and complexity of biological systems […]

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New Biological Theory

17 April 2024

New Biological Theory

New issue of biological theory with a thematic section on biological agency, including paper by Louis Virenque & Matteo Mossio on agency in biological autonomy, Andrew Pickering on agency in Science Studies, Samir Okasha on agency and evolution, and a commentary essay by Lenny Moss. All essays available in open-access here.

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New paper (2023): Ecosystem health and malfunctions: an organisational perspective

2 April 2024

New paper (2023): Ecosystem health and malfunctions: an organisational perspective

Published open-access in Biology and Philosophy Abstract: A recent idea of “ecosystem health” was introduced in the 1970s and 1980s to draws attention to the fact that ecosystems can become ill because of a reduction of properties such as primary productivity, functions and diversity of interactions among system components. Starting from the 1990s, this idea […]

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